Case Reports in Pulmonology (Jan 2019)

Pneumocystis jirovecii Pneumonia in an Immunocompetent Japanese Man: A Case Report and Literature Review

  • Hiromi Ide,
  • Yoshikazu Yamaji,
  • Kazunori Tobino,
  • Masanobu Okahisa,
  • Kojin Murakami,
  • Yuki Goto,
  • Takuto Sueyasu,
  • Saori Nishizawa,
  • Kohei Yoshimine,
  • Miyuki Munechika,
  • Masafumi Oya,
  • Yuka Hiraki

DOI
https://doi.org/10.1155/2019/3981681
Journal volume & issue
Vol. 2019

Abstract

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We herein report the case of a 37-year-old immunocompetent man who died from Pneumocystis jirovecii pneumonia (PCP). He was initially treated for an acute exacerbation of interstitial pneumonia; however, the elevation of the patient’s serum (1-3) β-D glucan (BG) level suggested the possibility of PCP and sulfamethoxazole trimethoprim was added. A postmortem pathological examination and retrospective Grocott's methenamine silver (GMS) staining of the bronchoalveolar lavage fluid (BALF), which was obtained on the day of admission, revealed PCP. The present case suggests that it is essential to perform a BG assay and GMS staining of BALF specimens when patients show diffuse ground-glass opacity on chest computed tomography, regardless of their immune status.