Risk factors of textbook outcome in laparoscopic pancreatoduodenectomy: results from a prospective high-volume center study

Abstract

Abstract Objective Achieving textbook outcome (TO) implies a smooth recovery post-operation without specified composite complications. This study aimed to evaluate TO in laparoscopic pancreaticoduodenectomy (LPD) and identify independent risk factors associated with achieving TO. Methods We conducted a retrospective analysis of data from a randomized controlled trial on LPD at West China Hospital (ChiCTR1900026653). Patients were categorized into the TO and non-TO groups. Perioperative variables were compared between these groups. Multivariate logistic regression was utilized to identify the risk factors. Results A total of 200 consecutive patients undergoing LPD were included in this study. TO was achieved in 82.5% (n = 165) of the patients. Female patients (OR: 2.877, 95% CI: 1.219–6.790; P = 0.016) and those with a hard pancreatic texture (OR: 2.435, 95% CI: 1.018–5.827; P = 0.046) were associated with an increased likelihood of achieving TO. Conclusions TO can be achieved in more than 80% of patients in a high-volume LPD center. Independent risk factors associated with achieving TO included gender (male) and pancreatic texture (soft).

Keywords

• Laparoscopic pancreaticoduodenectomy
• Textbook Outcome
• High-volume center
• Risk factors
• Complications