Study of matrix metalloproteinases and their tissue inhibitor in patients with ovarian tumors

Abstract

We studied main matrix metalloproteinases (MMP) and their tissue inhibitors in tumors and blood serum of ovarian cancer, benign and borderline tumor patients. We revealed a coordinate increase of MMP-7 tumor expression and serum concentration in ovarian cancer that indicates it’s role as potential serological marker for ovarian cancer.

Keywords

• ovarian cancer
• matrix metalloproteinase
• tissue matrix metalloproteinase inhibitors