The Use of Selected Biomarkers, Phagocytic and Cholinesterase Activity to Detect the Effects of Dimethoate on Marine Mussel (Mytilus edulis)

Hayati Journal of Biosciences. 2008;15(1):32-38

 

Journal Homepage

Journal Title: Hayati Journal of Biosciences

ISSN: 1978-3019 (Print); 2086-4094 (Online)

Publisher: Bogor Agricultural University

Society/Institution: Institut Pertanian Bogor

LCC Subject Category: Science: Biology (General)

Country of publisher: Indonesia

Language of fulltext: English, Indonesian

Full-text formats available: PDF

 

AUTHORS

KHUSNUL YAQIN
BIBIANA WIDIATI LAY
ETTY RIANI
ZAINAL ALIM MASUD
PETER-DIEDRICH HANSEN

EDITORIAL INFORMATION

Peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 24 weeks

 

Abstract | Full Text

Effects of organophosphorous pesticide, dimethoate on blue mussels, Mytilus edulis using selected biomarkers have been studied. Mussels were exposed to serial dilutions of dimethoate, 7.88, 15.75, 31.35, and 63.00 µg/l including positive and negative controls for 14 days. The suppression effects of dimethoate on phagocytic activity significantly occurred at two lowest concentrations of dimethoate (7.88 and 15.75 µg/l), but stimulation effects significantly emerged at the following highest concentrations (31.35 and 63.00 µg/l). The declining tendency of the cholinesterase (ChE) activity (23% lower than the control) appeared when mussels exposed to 7.88 and 15.75 µg/l dimethoate. Moreover, the significant inhibition of the ChE activity occurred at 31.35 µg/l dimethoate exposure. This study suggested that the phagocytic and the ChE activity are useful biomarkers for assessing the affects of organophosporous pesticide, dimethoate on neuro-immune system of blue mussels, M. edulis.