Using a network of meteor radar observations, observational evidence of polar-to-tropical mesospheric coupling during the 2018 major sudden stratosphere warming (SSW) event in the northern hemisphere is presented. In the tropical lower mesosphere, a maximum zonal wind reversal (−24 m/s) is noted and compared with that identified in the extra-tropical regions. Moreover, a time delay in the wind reversal between the tropical/polar stations and the mid-latitudes is detected. A wide spectrum of waves with periods of 2 to 16 days and 30–60 days were observed. The wind reversal in the mesosphere is due to the propagation of dominant intra-seasonal oscillations (ISOs) of 30–60 days and the presence and superposition of 8-day period planetary waves (PWs). The ISO phase propagation is observed from high to low latitudes (60° N to 20° N) in contrast to the 8-day PW phase propagation, indicating the change in the meridional propagation of winds during SSW, hence the change in the meridional circulation. The superposition of dominant ISOs and weak 8-day PWs could be responsible for the delay of the wind reversal in the tropical mesosphere. Therefore, this study has strong implications for understanding the reversed (polar to tropical) mesospheric meridional circulation by considering the ISOs during SSW.