Clinical applicability of biologically effective dose calculation for spinal cord in fractionated spine stereotactic body radiation therapy

Abstract

Background. The aim of the study was to investigate whether biologically effective dose (BED) based on linearquadratic model can be used to estimate spinal cord tolerance dose in spine stereotactic body radiation therapy (SBRT) delivered in 4 or more fractions.

Keywords

• biologically effective dose
• spine stereotactic body radiation therapy
• spinal cord
• tolerance dose
• linear quadratic model