PLoS ONE (Jan 2024)

The effect of multi-component exercise on cognition function in patients with diabetes: A systematic review and meta-analysis.

  • Zhiyuan Sun,
  • Hualei Liu,
  • Min Yan,
  • Haiqing Zeng,
  • Yiping Hu,
  • Xuewen Tian,
  • Dewei Mao

DOI
https://doi.org/10.1371/journal.pone.0304795
Journal volume & issue
Vol. 19, no. 6
p. e0304795

Abstract

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BackgroundThis meta-analysis investigated the influence of exercise on cognitive function in people living with diabetes.MethodsStringent criteria for literature inclusion and exclusion were defined. Searches were conducted across four English databases to gather randomized controlled trials investigating exercise interventions for cognitive function in people living with diabetes. Outcome indicators from 1193 subjects across 12 articles were analyzed using RevMan 5.4 software.ResultsExercise intervention demonstrated the ability to mitigate cognitive decline in people living with diabetes, with a combined effect size (standardized mean difference) of 0.91, 95% CI: 0.28, 1.54, P 40 minutes, exercise frequency >4 times per week, and sustained exercise for >6 months were paramount, all with P ConclusionExercise intervention emerges as a viable strategy for delaying cognitive decline in people living with diabetes. Its efficacy is subject to modulation by various variables. Optimal intervention includes multi-component exercise, individual sessions lasting 40-60 minutes, exercising >4 times a week, and continuous exercise for over 6 months.