Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus

Abstract

In experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclophosphamide damaged liver, as well as increase the antimetastatic effect of cytostatics. Water-soluble polysaccharides from Acorus calamus restore most efficiently biochemical disturbances at cyclophosphamide intoxication.

Keywords

• полисахариды
• циклофосфан
• ферменты печени