An Incidental Finding of AL‑associated Amyloidosis Presenting as Gastric Ulcers

Abstract

Gastrointestinal tract amyloidosis has been reported in rare instances and related symptoms are usually nonspecific to the disease process. We present a patient who initially had melena on anticoagulation and endoscopy revealed a bleeding gastric ulcer. Hemostasis was achieved. The patient had a recurrence of symptoms despite being off anticoagulation months later and at that time repeat endoscopy showed multiple gastric ulcers with surrounding friable mucosa. Biopsy results were significant for light chain associated‑amyloidosis. This case represents a rare cause of gastric ulcer.

Keywords

• gastric amyloid
• gastrointestinal bleed
• light‑chain amyloid