Emerging Infectious Diseases (Jul 2015)

Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus

  • Irene Ramos,
  • Mena Mansour,
  • Teddy J. Wohlbold,
  • Megan E. Ermler,
  • Ariana Hirsh,
  • Jonathan A. Runstadler,
  • Ana Fernandez-Sesma,
  • Florian Krammer

DOI
https://doi.org/10.3201/eid2107.141755
Journal volume & issue
Vol. 21, no. 7
pp. 1197 – 1201

Abstract

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Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.

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