P1473: CLINICALLY RELEVANT HEMOGLOBIN RESPONSE IN ADULTS WITH PYRUVATE KINASE DEFICIENCY TREATED WITH MITAPIVAT – A SUB-ANALYSIS OF THE ACTIVATE TRIAL

• Hanny Al-Samkari,
• Rachael F. Grace,
• Andreas Glenthøj,
• Wilma Barcellini,
• Madeleine Verhovsek,
• Jennifer A. Rothman,
• Marta Morado,
• Mark Layton,
• Oliver Andres,
• Frédéric Galactéros,
• Koichi Onodera,
• Satheesh Chonat,
• Rengyi Xu,
• Bryan Mcgee,
• Melissa Dibacco,
• Jaime Morales,
• Eduard van Beers

Affiliations

Hanny Al-Samkari

1 Massachusetts General Hospital, Harvard Medical School, Division of Hematology, Boston, United States

Rachael F. Grace

2 Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, United States

Andreas Glenthøj

3 Copenhagen University Hospital - Rigshospitalet, Danish Red Blood Cell Center, Department of Hematology, Copenhagen, Denmark

Wilma Barcellini

4 Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

Madeleine Verhovsek

5 McMaster University, Hamilton, Canada

Jennifer A. Rothman

6 Duke University Medical Center, Durham, United States

Marta Morado

7 Hospital Universitario La Paz, Hematology Department, Madrid, Spain

Mark Layton

8 Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

Oliver Andres

9 University of Würzburg, Department of Paediatrics, Würzburg, Germany

Frédéric Galactéros

10 CHU Henri Mondor, Unité des Maladies Génétiques du Globule Rouge, Creteil, France

Koichi Onodera

11 Tohoku University Hospital, Sendai, Japan

Satheesh Chonat

12 Emory University, Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta and Department of Pediatrics, Atlanta, United States

Rengyi Xu

13 Agios Pharmaceuticals, Inc., Cambridge, United States

Bryan Mcgee

13 Agios Pharmaceuticals, Inc., Cambridge, United States

Melissa Dibacco

13 Agios Pharmaceuticals, Inc., Cambridge, United States

Jaime Morales

13 Agios Pharmaceuticals, Inc., Cambridge, United States

Eduard van Beers

14 University Medical Center Utrecht, Utrecht University, Center for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, Utrecht, The Netherlands