A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids

Abstract

A patient with antisynthetase syndrome with pulmonary and muscular involvement was treated with immunosuppressive agents without corticosteroids. Rituximab was added to mycophenolate mofetil therapy with improvement in lung functional and imaging findings and normalization of creatine kinase levels.

Keywords

• antisynthetase syndrome
• interstitial lung disease
• polymyositis/dermatomyositis
• idiopathic inflammatory myopathy
• mycophenolate mofetil
• rituximab
• corticosteroids.