Structural and Synthetic Aspects of Small Ring Oxa- and Aza-Heterocyclic Ring Systems as Antiviral Activities
Sibasish Manna,
Koushik Das,
Sougata Santra,
Emily V. Nosova,
Grigory V. Zyryanov,
Sandipan Halder
Affiliations
Sibasish Manna
Department of Chemistry, Visvesvaraya National Institute of Technology, Nagpur 440010, India
Koushik Das
Department of Chemistry, Visvesvaraya National Institute of Technology, Nagpur 440010, India
Sougata Santra
Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, 19 Mira Street, 620002 Yekaterinburg, Russia
Emily V. Nosova
Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, 19 Mira Street, 620002 Yekaterinburg, Russia
Grigory V. Zyryanov
Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, 19 Mira Street, 620002 Yekaterinburg, Russia
Sandipan Halder
Department of Chemistry, Visvesvaraya National Institute of Technology, Nagpur 440010, India
Antiviral properties of different oxa- and aza-heterocycles are identified and properly correlated with their structural features and discussed in this review article. The primary objective is to explore the activity of such ring systems as antiviral agents, as well as their synthetic routes and biological significance. Eventually, the structure–activity relationship (SAR) of the heterocyclic compounds, along with their salient characteristics are exhibited to build a suitable platform for medicinal chemists and biotechnologists. The synergistic conclusions are extremely important for the introduction of a newer tool for the future drug discovery program.
