Red blood cell transfusion and skeletal muscle tissue oxygenation in anaemic haematologic outpatients

Abstract

Stored red blood cells (RBCs) accumulate biochemical and biophysical changes, known as storage lesion. The aim of this study was to re-challenge current data that anaemia in chronically anaemic haematology patients is not associated with low skeletal muscle tissue oxygen (StO2), and that RBC storage age does not influence the tissue response after ischaemic provocation, using near-infrared spectroscopy.

Keywords

• skeletal muscle
• tissue oxygenation
• red blood cells
• transfusion
• storage lesion