Memorias do Instituto Oswaldo Cruz (Aug 2010)

Circulation of hantaviruses in the influence area of the Cuiabá-Santarém Highway

  • Daniele BA Medeiros,
  • Elizabeth S Travassos da Rosa,
  • Aparecido AR Marques,
  • Darlene B Simith,
  • Adriana R Carneiro,
  • Jannifer O Chiang,
  • Ivy TE Prazeres,
  • Pedro FC Vasconcelos,
  • Márcio RT Nunes

DOI
https://doi.org/10.1590/S0074-02762010000500011
Journal volume & issue
Vol. 105, no. 5
pp. 665 – 671

Abstract

Read online

We describe evidence of circulation of hantaviruses in the influence area of the Santarém-Cuiabá Highway (BR-163) in the Brazilian Amazon through the prevalence of specific antibodies against hantaviruses in inhabitants living in four municipalities of this area: Novo Progresso (2.16%) and Trairão (4.37%), in state of Pará (PA), and Gua-rantã do Norte (4.74%) and Marcelândia (9.43%), in state of Mato Grosso. We also demonstrate the ongoing association between Castelo dos Sonhos virus (CASV) and hantavirus pulmonary syndrome (HPS) cases in the Castelo dos Sonhos district (municipality of Altamira, PA) and the first report of CASV in the municipalities of Novo Progresso and Guarantã do Norte. The results of this work highlight the risk for a possible increase in the number of HPS cases and the emergence of new hantavirus lineages associated with deforestation in this Amazonian area after the conclusion of paving works on BR-163 Highway.

Keywords