College of Medicine at the University of Vermont, Burlington, VT, USA
Brendan Campbell
University of Vermont Medical Center, Burlington, VT, USA
Michael Bazylewicz
University of Vermont Medical Center and College of Medicine at the University of Vermont, Burlington, VT, USA
William D. Brown
College of Medicine at the University of Vermont, Burlington, VT, USA
Devika Singh
University of Vermont Medical Center and College of Medicine at the University of Vermont, Burlington, VT, USA
Timothy Whitman
University of Vermont Medical Center and College of Medicine at the University of Vermont, Burlington, VT, USA
W. Kemper Alston
University of Vermont Medical Center and College of Medicine at the University of Vermont, Burlington, VT, USA
Adam Ulano
University of Vermont Medical Center and College of Medicine at the University of Vermont, Burlington, VT, USA
Benjamin Sawatzky
University of Vermont Medical Center and College of Medicine at the University of Vermont, Burlington, VT, USA
Andrew J. Hale
University of Vermont Medical Center and College of Medicine at the University of Vermont, Burlington, VT, USA; Correspondence to: University of Vermont Medical Center, Infectious Disease Unit, 111 Colchester Avenue, Mailstop 115 SM2, Burlington, VT 05401, USA.
The authors present the case of a 57-year-old male with a large polymicrobial brain abscess complicated by eruption into the intraventricular space. He was treated with parenteral ampicillin, cefepime, and metronidazole and adjuvant intraventricular vancomycin/gentamicin as well as surgical debridement. The authors discuss the diagnosis, treatment, and prognosis of brain abscesses, with a focus on prior cases with pyogenic ventriculitis and those treated with intraventricular antimicrobials.
