Endothelial function in normal and pathological conditions

Abstract

The article presents the data on the state of endothelial function in the normally and in various diseases and conditions. The basic functions of endothelium in modulation of vascular tone, atrombogenicity and thrombogenicity of the vascular wall, regulation of vascular wall adhesion, regulation of vascular growth are described. The main causes leading to the formation of endothelial dysfunction and the mechanisms underlying it are highlighted. Numerous studies on the evaluation of endothelial function in various diseases are presented. The basic methods of drug and non-drug correction of endothelial dysfunction are presented.

Keywords

• endothelial function
• endothelial dysfunction
• chronic diseases