Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing

Ting-Wei Wang; Hsiao-Wei Chu; Lin Chou; Yen-Ling Sung; Yuan-Ta Shih; Po-Chun Hsu; Hao-Min Cheng; Shien-Fong Lin

doi:10.3390/s21051600

Sensors (Feb 2021)

Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing

Ting-Wei Wang,
Hsiao-Wei Chu,
Lin Chou,
Yen-Ling Sung,
Yuan-Ta Shih,
Po-Chun Hsu,
Hao-Min Cheng,
Shien-Fong Lin

Affiliations

Ting-Wei Wang: Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan
Hsiao-Wei Chu: Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan
Lin Chou: Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan
Yen-Ling Sung: Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan
Yuan-Ta Shih: Research and Development Department VI, Smart Healthcare BU, Leadtek Research Inc., New Taipei 23511, Taiwan
Po-Chun Hsu: Research and Development Department VI, Smart Healthcare BU, Leadtek Research Inc., New Taipei 23511, Taiwan
Hao-Min Cheng: Center for Evidence-Based Medicine, Department of Medical Education, Taipei Veterans General Hospital, Taipei 11217, Taiwan
Shien-Fong Lin: Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan

DOI: https://doi.org/10.3390/s21051600
Journal volume & issue: Vol. 21, no. 5
p. 1600

Abstract

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Continuous hemodynamic monitoring is important for long-term cardiovascular healthcare, especially in hypertension. The impedance plethysmography (IPG) based carotid pulse sensing is a non-invasive diagnosis technique for measuring pulse signals and further evaluating the arterial conditions of the patient such as continuous blood pressure (BP) monitoring. To reach the high-resolution IPG-based carotid pulse detection for cardiovascular applications, this study provides an optimized measurement parameter in response to obvious pulsation from the carotid artery. The influence of the frequency of excitation current, electrode cross-sectional area, electrode arrangements, and physiological site of carotid arteries on IPG measurement resolution was thoroughly investigated for optimized parameters. In this study, the IPG system was implemented and installed on the subject’s neck above the carotid artery to evaluate the measurement parameters. The measurement results within 6 subjects obtained the arterial impedance variation of 2137 mΩ using the optimized measurement conditions, including excitation frequency of 50 kHz, a smaller area of 2 cm2, electrode spacing of 4 cm and 1.7 cm for excitation and sensing functions, and location on the left side of the neck. The significance of this study demonstrates an optimized measurement methodology of IPG-based carotid pulse sensing that greatly improves the measurement quality in cardiovascular monitoring.

Published in Sensors

ISSN: 1424-8220 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Technology: Chemical technology
Website: http://www.mdpi.com/journal/sensors

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