Effects of seasonal variations and meteorological factors on IVF pregnancy outcomes: a cohort study from Henan Province, China

Abstract

Abstract Objective To investigate whether seasonal variations and meteorological factors influence pregnancy outcomes in women undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment. Design Retrospective cohort study. Setting University-affiliated reproductive medical center. Subjects Women aged 0.050). Multivariate logistic regression analysis showed significant seasonal variation in clinical pregnancy (OR = 1.643, 95% CI = 1.203–2.243; P = 0.002), and that a higher daily average temperature at the time of ovulation induction increased the clinical pregnancy rate (OR = 1.012, 95% CI = 1.001–1.022; P = 0.031). Conclusions In women younger than 35 years who undergo IVF treatment, the season and ambient temperature on the date of the beginning of ovulation induction may have an impact on embryo development and clinical pregnancy.

Keywords

• IVF
• Season
• Temperature
• Embryonic development
• Pregnancy outcome