Revista de Saúde Pública (Jun 1971)
Hetacilina em dose única no tratamento da gonorréia Hetacillin in a single dose in the treatment of gonorrhoeae
Abstract
Foram tratados 155 pacientes do sexo masculino, portadores de uretrite gonocócica aguda, com 3,0 g de Hetacilina K por via oral (70 casos) ou 1,0 g do mesmo medicamento por via intramuscular (85 casos). Em 88,6% dos casos tratados pela via oral, e em 93% dos casos tratados com uma injeção intramuscular, o corrimento desapareceu em um tempo médio de 48 horas. Não foram observadas reações de intolerância ao medicamento.Schemes of treatment with one single parenteral injection or single oral dosis of a broad spectrum antibiotic - Hetacillin - has been employed in 155 patients with acute gonorrhoeae who were, then, followed-up during 15 days in the Service of VD of the School of Public Health, University of São Paulo. The diagnosis and control of the cases were performed through smears and cultures of the urethral discharge. Cure has been attained in 88,6% of 70 patients treated with 3.0 g of Hetacillin by oral route, in a single dosis, and in 93% of 85 patients treated with one single intramuscular injection of Hetacillin (1.0 g). Discharge has disappeared in an average of 48 hours in both schedules of treatment. No side effects or toxicity were observed.
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