Methylphenidate and Desipramine Toxicities

Abstract

A double-blind controlled study of medications in 12 children with ADHD at New York University and Stony Brook Schools of Medicine showed that nausea, vomiting, dry mouth, tremor, headache, anorexia, lassitude, and tachycardia occurred more frequently when methylphenidate (20 mg) and desipramine (148 mg/day) were combined in therapy compared to either medication alone.

Keywords

• methylphenidate
• desipramine
• drug therapy