1526 Nous-209 genetic vaccine encoding shared cancer neoantigens is safe and elicits robust immune response in healthy Lynch syndrome carriers: interim results from Phase 1 cancer interception trial

• Asad Umar,
• Jack Lee,
• Diane Liu,
• Eduardo Vilar,
• Ellen Richmond,
• Powel H Brown,
• Laura Antonucci,
• Marcia Cruz-Correa,
• Michael J Hall,
• Guido Leoni,
• Gabriella Cotugno,
• Irene Garzia,
• Elisa Scarselli,
• Araceli Garcia-Gonzalez,
• Loredana Siani,
• Sven Gogov,
• Laura Reyes Uribe,
• Morena D’Alise,
• Jason Willis,
• Gregory E Idos,
• Lana A Vornik,
• Luz Maria Rodriguez

Affiliations

Asad Umar

9National Cancer Institute, Bethesda, MD, USA

Jack Lee

7Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Diane Liu

7Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Eduardo Vilar

8Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Ellen Richmond

9National Cancer Institute, Bethesda, MD, USA

Powel H Brown

8Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Laura Antonucci

1Nouscom Srl, Rome, Italy

Marcia Cruz-Correa

3University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico

Michael J Hall

4Fox Chase Cancer Center, Philadelphia, PA, USA

Guido Leoni

1Nouscom Srl, Rome, Italy

Gabriella Cotugno

1Nouscom Srl, Rome, Italy

Irene Garzia

1Nouscom Srl, Rome, Italy

Elisa Scarselli

1Nouscom Srl, Rome, Italy

Araceli Garcia-Gonzalez

8Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Loredana Siani

1Nouscom Srl, Rome, Italy

Sven Gogov

6Nouscom AG, Basel, Switzerland

Laura Reyes Uribe

8Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Morena D’Alise

1Nouscom Srl, Rome, Italy

Jason Willis

2Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Gregory E Idos

5City of Hope Comprehensive Cancer Center, Duarte, CA, USA

Lana A Vornik

8Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Luz Maria Rodriguez

9National Cancer Institute, Bethesda, MD, USA