RGO: Revista Gaúcha de Odontologia (Jan 2008)

Stevens-Johnson syndrome associated with antimicrobial agent

  • Ivo Cavalcanti Pita Neto,
  • Antonio Azoubel Antunes,
  • Rafael Linard Avelar,
  • Thiago de Santana Santos,
  • Paulo Germano Carvalho Bezerra Falcão,
  • Edwaldo Dourado

Journal volume & issue
Vol. 56, no. 3
pp. 337 – 340

Abstract

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Among the severe reactions to medications, immune-mediated Mucocutaneous Disorders are widely represented. Steven-Johnson’s syndrome, or great multiform erythema, appears as a systemic disturbance, involving the skin and mucous membranes, and is related to several factors, such as, viral or bacterial infections and particularly the administration of medicines, in general painkillers and antibiotics. The objective of this article is report the onset of ulcerative vesicle –blister lesions in the regions of the lips, gums, tongue and genital mucosa membrane in a 26 year-old patient, a leukoderm man, being treated with sulfamethoxazole trimethoprim for a respiratory infection, after being diagnosed as having the Steven-Johnson syndrome. SSJ1 558187121279.

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