Pediatric Central Nervous System Tumors: Center Experience

Abstract

INTRODUCTION: Objective: The aim of this study is to evaluate the distribution of pediatric brain tumors diagnosed in our institution according to age, gender, localization, histological type and grade. METHODS: Materials and Methods: One hundred and nineteen children under 18 years of age, diagnosed with central nervous system tumor (CNS) in our department between 2011 january -2019 july is included in the study. Clinical follow-up was achieved through the archive files of the hospital data management system and the files of pediatric oncology department. RESULTS: Results: Of 119 patients who had a tumor diagnosis, 57 (48%) were female and 62 (52%) were male. Age distribution was as follows: 40 (34%) cases 0-5, 36 (30%) cases 6-10 and 43 (36%) cases 11-18 years of age. Fourty-two of the cases had a tumor with posterior fossa localization. Astrocytoma was the most frequent tumor type, followed by medulloblastoma and ependymoma. Fifty percent of the astrocytomas were pilocytic variant. DISCUSSION AND CONCLUSION: Conclusion: Our results were accordance with the literature. Childhood central nervous system tumors are the most common tumors after leukemia and the type, location, size and treatment methods of the tumor are very important for survival. Surgery has a very important role in the treatment and better results will be obtained when the follow-up and treatment modalities (CT and / or RT decision) of patients and disease-related analyzes are performed and given with a multidisciplinary approach.

Keywords

• central nervous system tumors
• pathological review
• who 2007 classification