Nature Communications (Jan 2018)

CKAMP44 modulates integration of visual inputs in the lateral geniculate nucleus

  • Xufeng Chen,
  • Muhammad Aslam,
  • Tim Gollisch,
  • Kevin Allen,
  • Jakob von Engelhardt

DOI
https://doi.org/10.1038/s41467-017-02415-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 13

Abstract

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The function of receptor desensitization in vivo is not well understood. Here, the authors show that deletion of CKAMP44, an AMPAR auxiliary protein that modulates desensitization of AMPAR currents, affects synaptic facilitation at retinogeniculate synapses and visually-evoked firing in awake mice.