Гинекология (May 2020)

Iatrogenic chimerism in a patient with Fanconi anemia and delayed puberty

  • Zaira Kh. Kumykova,
  • Irina A. Kiseleva,
  • Zalina K. Batyrova,
  • Olga A. Buyanovskaya

DOI
https://doi.org/10.26442/20795696.2020.2.200108
Journal volume & issue
Vol. 22, no. 2
pp. 35 – 37

Abstract

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The article presents a clinical case of delayed puberty in a 13-year-old girl with Fanconi anemia who was sent to the Department of gynecology of children and adolescents for removal of the sexual glands due to the detection of a Y-chromosome in the karyotype at the place of residence. A personalized multidisciplinary approach to the management of a patient with Fanconi anemia with the presence of the Y-chromosome in the karyotype against the background of delayed puberty allowed to identify iatrogenic chimerism and avoid unjustified castration.

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