Pathological study on some tissues of rat experimentally infected with Toxoplasma gondii

Abstract

ABSTRACT This study was conducted to isolate Toxoplasma gondii from aborted placentae of ewes, & follow up the histopathological changes that produced in some different organs such as liver, brain & eyes of rats which inoculated experimentally by suspension of the parasite. Histopathological changes in brain represented by presence of tachyzoites & tissue cyst at 30/45 days post infection associated with encephalomeningitis–while in liver, the lesions characterized by presence of perivascular & periductular cuffing of tachyzoites associated with pyknotic nuclei of hepatocytes. Moreover, in the eye tachyzoites & tissue cyst has been seen invaded in extraocular muscles, congestion of blood vessels with lymphocytic infiltration and retinochoroiditis, also has been seen.

Keywords

• rat experimentally infected
• toxoplasma gondii
• parasite