Nature Communications (Jul 2022)

A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys

  • Jiao Qu,
  • Fa Yang,
  • Tao Zhu,
  • Yingshuo Wang,
  • Wen Fang,
  • Yan Ding,
  • Xue Zhao,
  • Xianjia Qi,
  • Qiangmin Xie,
  • Ming Chen,
  • Qiang Xu,
  • Yicheng Xie,
  • Yang Sun,
  • Dijun Chen

DOI
https://doi.org/10.1038/s41467-022-31770-x
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 19

Abstract

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Non-human primates are attractive laboratory animal models that can accurately reflect some developmental and pathological features of humans. Here the authors chart a reference cell map of cynomolgus monkeys using both scATAC-seq and scRNA-seq data across multiple organs, providing insights into the molecular dynamics and cellular heterogeneity of this organism.