Surgeries (Sep 2023)

Acral Lentiginous Melanoma of the Thumb: Dermoscopy and Treatment

  • Antonella Tammaro,
  • Ganiyat Adenike Ralitsa Adebanjo,
  • Michail Sorotos,
  • Carmen Cantisani,
  • Camilla Chello,
  • Hans Peter Erasmus,
  • Francesca Romana Grippaudo,
  • Fabio Santanelli Di Pompeo,
  • Giovanni Pellacani

DOI
https://doi.org/10.3390/surgeries4040049
Journal volume & issue
Vol. 4, no. 4
pp. 503 – 510

Abstract

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Melanoma affecting glabrous skin is a challenging entity that needs to be managed by an interdisciplinary team of dermatologists, oncologists, and surgeons. The thin subcutaneous layer of glabrous skin, which speeds up its metastatic spread, is one of the key elements that contributes to the aggressiveness of this form of cutaneous cancer when identified in this anatomical region. Acral lentiginous melanoma is a rare melanocytic malignancy that is usually associated with ominous outcomes, especially in those with dark skin. Moreover, more extensive research is needed to elucidate the puzzle of molecular drivers and their relationship with thermal injury. We reported our experience in order to highlight the value of timely diagnosis and treatment.

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