Tropical Diseases, Travel Medicine and Vaccines (Apr 2018)

Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation

  • Kevin L. Schwartz,
  • Tiffany Chan,
  • Nanky Rai,
  • Kellie E. Murphy,
  • Wendy Whittle,
  • Michael A. Drebot,
  • Jonathan Gubbay,
  • Andrea K. Boggild

DOI
https://doi.org/10.1186/s40794-018-0062-8
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 7

Abstract

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Abstract Background Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. Case presentation A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in Trinidad presented with one-month of fever, headache, and myalgia with persistent viremia. Significant fetal abnormalities were identified at 14-week ultrasound, which is the earliest ultrasound to describe a severely affected fetus following Zika virus infection to our knowledge. Conclusions We discuss the implications of prolonged maternal viremia and the spectrum of congenital Zika syndrome detectable by fetal ultrasound.

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