Acetic acid-promoted condensation of o-phenylenediamine with aldehydes into 2-aryl-1-(arylmethyl)-1H-benzimidazoles under microwave irradiation

Abstract

An efficient and simple procedure was developed for the green synthesis of various 2-aryl-1-(arylmethyl)-1H-benzimidazoles in high yields by acetic acid-promoted condensation of o-phenylenediamine with aldehydes in air under microwave irradiation and transition metal catalyst-free conditions.

Keywords

• yl-1-(arylmethyl)-1H-benzimidazoles
• o-phenylenediamine
• aldehydes
• microwave irradiation
• acetic acid