Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome

• Anna J. Moyer,
• Fabian-Xosé Fernandez,
• Yicong Li,
• Donna K. Klinedinst,
• Liliana D. Florea,
• Yasuhiro Kazuki,
• Mitsuo Oshimura,
• Roger H. Reeves

Affiliations

Anna J. Moyer

Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

Fabian-Xosé Fernandez

Department of Psychology, University of Arizona, Tucson, AZ 85724, USA

Yicong Li

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

Donna K. Klinedinst

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

Liliana D. Florea

Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

Yasuhiro Kazuki

Division of Genome and Cellular Functions, Department of Molecular and Cellular Biology, School of Life Science, Faculty of Medicine and Chromosome Engineering Research Center, Tottori University, 86 Nishi-cho, Yonago, Tottori 683-8503, Japan

Mitsuo Oshimura

Chromosome Engineering Research Center, Tottori University, Yonago, Tottori 683-8503, Japan

Roger H. Reeves

Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA