BMC Genomics (Apr 2024)

Haplotype diversity of 17 Y-STR in the Iranian population

  • Mohammad Reza Eskandarion,
  • Arash Alipour Tabrizi,
  • Reza Shirkoohi,
  • Reza Raoofian,
  • Masume Naji,
  • Reza Pazhoomand,
  • Hooman Salari,
  • Bahram Samadirad,
  • Alireza Sabouri,
  • Mostafa Montazer Zohour,
  • Hadi Namazi,
  • Pegah Farhadi,
  • Zohre Baratieh,
  • Minoo Sayyari,
  • Maliheh Dadgarmoghaddam,
  • Esmat Safdarian,
  • Afrooz Nikbakht,
  • Farnaz Golshan,
  • Fatemeh Baybordi,
  • Elham Madhaji,
  • Shadi ShohodiFar,
  • Mohsen Tabasi,
  • Ramezan Mohebbi

DOI
https://doi.org/10.1186/s12864-024-10217-1
Journal volume & issue
Vol. 25, no. 1
pp. 1 – 8

Abstract

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Abstract The current study aimed to evaluate Y chromosome haplotypes obtained from 1353 unrelated Iranian males using the AmpFlSTRTM YfilerTM kit; 1353 out of the 1353 identified haplotypes were unique. The haplotype diversity (HD) and discriminating capacity (DC) values were 1.00000 and 0.997, respectively. Analysis of genetic distance was performed using molecular variance (AMOVA) and multidimensional scaling plots (MDS), revealing a statistically significant difference between the study population and previous data reported for other Iranian populations and other neighboring countries. The present findings are likely to be useful for forensic casework analyses and kinship investigations.

Keywords