Pipeline embolization devices for the treatment of nonsaccular aneurysms in pediatric patients

Jintao Han; Fei Liang; Yuxiang Zhang; Yupeng Zhang; Shikai Liang; Haoyu Zhu; Yuzhou Chang; Chao Ma; Lian Liu; Zichang Jia; Chuhan Jiang

doi:10.3389/fneur.2023.1115618

Frontiers in Neurology (Feb 2023)

Pipeline embolization devices for the treatment of nonsaccular aneurysms in pediatric patients

Jintao Han,
Fei Liang,
Yuxiang Zhang,
Yupeng Zhang,
Shikai Liang,
Haoyu Zhu,
Yuzhou Chang,
Chao Ma,
Lian Liu,
Zichang Jia,
Chuhan Jiang

Affiliations

Jintao Han: Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing, China
Fei Liang: Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing, China
Yuxiang Zhang: Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing, China
Yupeng Zhang: Department of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Shikai Liang: Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China
Haoyu Zhu: Department of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Yuzhou Chang: Department of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Chao Ma: Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China
Lian Liu: Department of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Zichang Jia: Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing, China
Chuhan Jiang: Department of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China

DOI: https://doi.org/10.3389/fneur.2023.1115618
Journal volume & issue: Vol. 14

Abstract

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ObjectivePediatric nonsaccular aneurysms are rare but challenging lesions; pipeline embolization devices (PEDs) are their potential treatment option. In this study, we aimed to evaluate the safety and efficacy of PEDs for treatment of these aneurysms.MethodsWe retrospectively selected pediatric patients with nonsaccular aneurysms treated using PEDs between June 2015 and July 2021 from our prospectively maintained database. For each patient, demographics, aneurysm characteristics, procedure details, and clinical and angiographic follow-up data were collected and summarized.ResultsThis study included 16 pediatric patients with 16 nonsaccular aneurysms treated with PEDs. A median clinical follow-up time of 1,376 days was achieved in 93.75% of the patients. The complication rate of the included patients was 25%, with two patients developing mass effect, one patient undergoing major ischemic stroke, and one patient experiencing stent foreshortening after the procedure. The complete occlusion rate of aneurysms without any neurologic sequelae was 93.33%, with a median angiographic follow-up period of 246 days. The mortality rate was 6.25%.ConclusionsThe use of PEDs to treat pediatric nonsaccular aneurysms is feasible, with a high rate of complete occlusion of the aneurysm and favorable follow-up outcomes.

Published in Frontiers in Neurology

ISSN: 1664-2295 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system
Website: https://www.frontiersin.org/journals/neurology/

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