Tuberculous meningitis and septic shock due to miliary tuberculosis in Down syndrome: a case report

Abstract

Introduction: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Only 1% of tuberculosis cases present as septic shock. Case presentation: A 41-year-old male with a history of trisomy 21. The condition began with holocranial headache, paresis of the left upper extremity, and paresis of the ipsilateral pelvic limb. As he did not present perfusing blood pressure, management with norepinephrine was initiated. Sampling showed positivity for M. tuberculosis. Antituberculous therapy planned for 12 months was started and dexamethasone was added. Conclusion: In patients with Down syndrome, it is necessary to intentionally look for extrapulmonary forms.

Keywords

• Tuberculosis. Tuberculous meningitis. Tuberculosis septic shock. Miliary tuberculosis. Down syndrome.