Review: Strategies and technologies in preventing regulated and emerging mycotoxin co-contamination in forage for safeguarding ruminant health

Abstract

Ruminants are often considered less susceptible to mycotoxins than monogastrics, owing to rumen microflora converting mycotoxins to less toxic compounds or several compounds present in the rumen-reticulum compartment, being able to bind the mycotoxin “mother” molecule that make them unavailable for absorption process in the gastro-intestinal tract of host animals. However, if ruminants consume feed contaminated by mycotoxins for long periods, their growth, development, and fertility can be compromised. Among regulated mycotoxins, the most studied and known for their effects are aflatoxins (AFs) AFB1, AFB2, AFG1 and AFG2, as well as the AFM1 for its high importance in dairy sector, deoxynivalenol (DON) and its metabolites 3/15 acetyl-DON and 3-glucoside DON, T-2 and HT-2 toxins, zearalenone, fumonisins, in particular that belong to the B class, and ochratoxin A. Furthermore, because of the emergence of multiple emerging mycotoxins that are detectable in feed utilised in ruminant diets, such as ensiled forage, there is now a growing focus on investigating these compounds by the scientific community to deepen their toxicity for animal health. Despite the enhancement of research, it is remarkable that there is a paucity of in vivo trials, as well as limited studies on nutrient digestibility and the impact of these molecules on rumen and intestinal functions or milk yield and quality. In this review, recent findings regarding the occurrence of regulated and emerging mycotoxins in forage and their possible adverse effects on dairy cattle are described, with special emphasis on animal performance and on rumen functionality.

Keywords

• Animal health
• Feed safety
• Forage
• Fungi
• Volatile organic compounds