Nature Communications (Nov 2017)

Transient cardiomyocyte fusion regulates cardiac development in zebrafish

  • Suphansa Sawamiphak,
  • Zacharias Kontarakis,
  • Alessandro Filosa,
  • Sven Reischauer,
  • Didier Y. R. Stainier

DOI
https://doi.org/10.1038/s41467-017-01555-8
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 15

Abstract

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Cell fusion regulates several physiological events, for example, fusion of myoblasts in skeletal muscle formation, but it is unclear if this process occurs in the heart. Here, the authors use transgenic reporters in zebrafish to show transient cardiomyocyte fusion, modulating cardiac development and function.