Prevalence of neurodegenerative/demyelinating disorders in patients with achalasia

Abstract

Esophageal achalasia is a primary motility disorder. Although the exact pathogenesis is unknown, autoimmune, and neurodegenerative processes seem to be involved similarly to neurodegenerative and/or demyelinating disorders (NDDs). We hypothesized that the prevalence of NDD may be higher among patients with achalasia and vice versa as the background pathogenetic mechanisms are similar.

Keywords

• achalasia
• demyelinating process
• neurodegeneration