Global Journal of Medicine and Public Health (May 2024)
Comparative study of efficacy of methyldopa vs labetalol in the management of pregnancy induced hypertension in respect to maternal and perinatal outcomes
Abstract
This study was a prospective, comparative study, used to determine & compare the efficacy of treatment with methyldopa vs labetalol with respect to maternal – perinatal benefits and adverse effects. Conducted in the Department of Obstetrics and Gynaecology in Vivekananda Institute of Medical Science, Ramakrishna Mission Seva Pratishthan, a total 425 patients were taken into the study. The patients were divided into two groups by simple random sampling method. They were monitored throughout pregnancy and delivery till 7 days postpartum. The results obtained were divided in 3 sections Effective BP control, Maternal outcome, Perinatal outcome, which were again divided into three periods – Antepartum, Intrapartum and Postpartum for better elaboration. The study revealed that labetalol helps in quicker and more efficacious control of BP in mothers developing gestational hypertension with chances of developing preeclampsia – eclampsia syndrome.
