PLoS ONE (Jan 2021)

Analysis of the composition and antioxidant status of breast milk in women giving birth prematurely and on time.

  • Agnieszka Chrustek,
  • Agnieszka Dombrowska-Pali,
  • Dorota Olszewska-Słonina

DOI
https://doi.org/10.1371/journal.pone.0255252
Journal volume & issue
Vol. 16, no. 7
p. e0255252

Abstract

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BackgroundBreastfeeding with mother's milk is the best form of nutrition not only for newborn babies, but especially for premature babies, due to the health benefits of taking human food.ObjectivesThe aim of the study was to examine the basic composition, cortisol concentration and antioxidant status of breast milk samples from women giving birth before 37 weeks of pregnancy and comparing it with milk samples from women giving birth after 37 weeks of pregnancy.MethodsThe material for the study was milk taken from women giving birth before and after 37 weeks of pregnancy. The basic composition of breast milk was determined using a MIRIS analyzer, cortisol concentration in samples by an enzyme-linked immunosorbent test and their total antioxidant status was assessed by DPPH and FRAP methods.ResultsIt has been shown that the concentration of cortisol in samples of human milk in the group of women giving birth before 37 weeks was 13.95 ng / ml [4,71-86,84], while in the group of women giving birth after week 37 of pregnancy-10.31 ng / ml [2.35-39-02] (p = 0.014), while% inhibition of DPPH was 65.46% and 58.30%, respectively (p = 0.014).ConclusionsMilk from women giving birth prematurely is qualitatively different from the milk of women giving birth on time. The total antioxidant status of preterm milk is higher than term milk, which promotes the development of premature babies. Higher cortisol levels in samples from women giving birth before 37 weeks of pregnancy may stimulate the digestive system.