Pain Research and Management (Jan 2009)

Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty

  • Hance Clarke,
  • Sara Pereira,
  • Deborah Kennedy,
  • Ian Gilron,
  • Joel Katz,
  • Jeffrey Gollish,
  • Joseph Kay

DOI
https://doi.org/10.1155/2009/930609
Journal volume & issue
Vol. 14, no. 3
pp. 217 – 222

Abstract

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BACKGROUND: Moderate to severe pain after total knee arthroplasty often interferes with postoperative rehabilitation and delays discharge from hospital. The present study examined the effects of a four-day postoperative gabapentin (GBP) regimen versus placebo on opioid consumption, pain scores and knee flexion, as well as adverse effects, after total knee arthroplasty.