Correlation Between Psoas Muscle Area and Clinical Frailty Score in Patients with Transcatheter Aortic Valve Replacement

Abstract

Introduction:Transcatheter aortic valve implantation (TAVI) has been widely used in patients with high-risk aortic valve stenosis. Frailty is a parameter that significantly affects prognosis in cardiovascular diseases. In the clinic, the identification and validation of simple and inexpensive frailty evaluation methods are important. Our aim is to determine the importance of a simple and inexpensive clinical evaluation tool that can be used in patients with TAVI by examining the correlation between the “clinical frailty scale (CFS)” and “the psoas muscle area (PMA)”, which is a quantitative indicator of fraility.Methods:CFS was determined by clinical evaluation of 61 patients who underwent TAVI and PMA was calculated by computed tomography scan.Results:A significant correlation was found between the CFS and PMA values of the patients in the correlation analysis (r=-0.970, p<0.001). Patients with early poor outcome had higher CFS values (6.0±0.9 vs 3.79±1.4; p<0.000) and lower PMA values (3.03±0.3 vs. 6.48±1.2; p<0.000).Conclusion:In short and long term prognosis of all cardiovascular diseases, frailty is an important guidance. CFS, which is clinically simple, easy-to-apply and inexpensive, is highly correlated with PMA, which is a quantitative indicator of fraility and closely related to prognosis in TAVI.

Keywords

• Transcatheter aortic valve implantation
• frailty
• prognosis