Gene Therapy Applications in Dentistry: A Review

Abstract

Gene therapy involves transfer of new genetic material or manipulation of the existing material for the purpose of treating human disease. It involves transfer of genetic material – ex vivo and in vivo and may conceivably revolutionize clinical practice in the coming years. Although progress has chiefly been in the medical domain, research has moved to various dental conditions as well. This review is presented to highlight various applications of gene therapy in dentistry in the areas such as salivary gland disorders, chronic pain, DNA vaccines, bone repair, implantology, head and neck cancer, orthodontic therapy, periodontal repair and tooth regrowth.

Keywords

• Bone Repair
• Gene transfer techniques
• Growth factor
• Neoplasms