Translational Neuroscience (May 2023)

miR-101-3p improves neuronal morphology and attenuates neuronal apoptosis in ischemic stroke in young mice by downregulating HDAC9

  • Zhang Mengru,
  • Wang Jianjun,
  • Li Jinfang,
  • Kong Fanxin,
  • Lin Songjun

DOI
https://doi.org/10.1515/tnsci-2022-0286
Journal volume & issue
Vol. 14, no. 1
pp. 15 – 39

Abstract

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MiRNAs play a key role in ischemic stroke (IS). Although miR-101-3p can participate in multiple disease processes, its role and mechanism in IS are not clear. The aim of the present study was to observe the effect of miR-101-3p activation on IS in young mice and the role of HDAC9 in this effect.

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