Blink-sensing glasses: A flexible iontronic sensing wearable for continuous blink monitoring

Rui Chen; Zhichao Zhang; Ka Deng; Dahu Wang; Hongmin Ke; Li Cai; Chi-wei Chang; Tingrui Pan

iScience (May 2021)

Blink-sensing glasses: A flexible iontronic sensing wearable for continuous blink monitoring

Rui Chen,
Zhichao Zhang,
Ka Deng,
Dahu Wang,
Hongmin Ke,
Li Cai,
Chi-wei Chang,
Tingrui Pan

Affiliations

Rui Chen: Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; School of Computer Science, University of Chinese Academy of Sciences, Beijing 100049, China
Zhichao Zhang: Micro-Nano Innovations (MiNI) Laboratory, Department of Biomedical Engineering, University of California, Davis, CA 95616, USA; TacSense, Inc., Woodland, CA 95776, USA
Ka Deng: Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Shenzhen Engineering Laboratory of Single-molecule Detection and Instrument Development Shenzhen 518055, China
Dahu Wang: Department of Ophthalmology, LongHua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Hongmin Ke: Department of Ophthalmology, Shenzhen University General Hospital, Shenzhen University Clinical Medical Academy, Shenzhen 518055, China
Li Cai: Department of Ophthalmology, Shenzhen University General Hospital, Shenzhen University Clinical Medical Academy, Shenzhen 518055, China
Chi-wei Chang: Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Tingrui Pan: Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Micro-Nano Innovations (MiNI) Laboratory, Department of Biomedical Engineering, University of California, Davis, CA 95616, USA; Shenzhen Engineering Laboratory of Single-molecule Detection and Instrument Development Shenzhen 518055, China; Suzhou Institute for Advanced Research, University of Science and Technology of China, Suzhou 215123, China; Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei 230026, China; Corresponding author

Journal volume & issue: Vol. 24, no. 5
p. 102399

Abstract

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Summary: Blink reflex has long been considered closely related to physiological states, from which abundant information on ocular health and activities can be revealed. In this study, a smart glasses wearable has been developed, incorporating a flexible and sensitive pressure sensor, to monitor blink patterns by continuously detecting ocular muscular movements, referred to as blink-sensing glasses. By applying the emerging flexible iontronic sensing (FITS) sensor with the sensitivity of 340 pF/mmHg, the skin pressure variations induced by movements of the orbicularis oculi muscles can be monitored in real time. The blink-sensing glasses can successfully capture blink patterns with a high accuracy of 96.3% and have been used to differentiate the blink features from both dry-eye subjects and healthy controls. This device can be potentially used as a new clinical and research monitoring tool for continuous eye blink analysis, while providing patients with high comfortableness in long-term ambulatory and home settings.

Published in iScience

ISSN: 2589-0042 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science
Website: http://www.cell.com/iscience/home

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