Establishment of a spontaneous ventilation anesthesia model for beagle dogs
Yuan Zeng,
Hui Liu,
Fei Cui,
Weipeng Cai,
Jianxing He,
Jun Liu
Affiliations
Yuan Zeng
Department of Thoracic Surgery & Department of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China
Hui Liu
Department of Anesthesia, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
Fei Cui
Department of Thoracic Surgery & Department of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China
Weipeng Cai
Department of Cardiothoracic Surgery, Shantou Central Hospital, Shantou, China
Jianxing He
Department of Thoracic Surgery & Department of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China; Corresponding authors at: Department of Thoracic Surgery & Department of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, No. 151, Yanjiang Rd, Guangdong Province, Guangzhou 510120, China.
Jun Liu
Department of Thoracic Surgery & Department of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China; Corresponding authors at: Department of Thoracic Surgery & Department of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, No. 151, Yanjiang Rd, Guangdong Province, Guangzhou 510120, China.
While spontaneous ventilation (SV) anesthesia is in use for clinical patients, there is still little systematic experimental research into its basic aspects. The rabbit SV model that we established previously has some limitations including the model being too small, differences in anesthetic drugs and anesthesia procedures, so we set out to establish an SV anesthesia model for beagle dogs. • Single lumen tracheal intubation was performed on beagles connecting a ventilator, and the anesthetic dosage was adjusted for spontaneous ventilation before surgery. • 5 mL of 1 % lidocaine was applied as a local infiltration anesthesia at the surgical incision. • After thoracotomy, 5 mL of 1% lidocaine was sprayed onto the surface of the lungs and a T3–T7 intercostal nerve block (1:1 2 % lidocaine:0.75 % ropivacaine) was performed.
