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THE THYMUS GLAND (THYMUS) ASPECTS IN CHILDREN (PART V). HORMONAL AND MORPHOLOGICAL INTERACTION OF THE THYMUS WITH THE NEUROENDOCRINE SYSTEM AND IN PARTICULAR WITH SOMATOTROPIC HORMONE AND INSULIN-LIKE GROWTH FACTOR

  • Наталья Николаевна Миняйлова,
  • Юрий Иванович Ровда,
  • Сергей Фадеевич Зинчук,
  • Александра Евгеньевна Климанова,
  • Вероника Павловна Строева,
  • Наталья Степановна Черных

Journal volume & issue
Vol. 23, no. 1
pp. 11 – 20

Abstract

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The literature review includes data on the interaction of the thymus with the neuroendocrine system, hormonal and morphological relations between the thymus, somatotropic hormone and insulin-like growth factor (IGF), the effect of growth hormone (GH) to age-related thymus involution. The results of experimental studies and contradictory data to the effect of the somatotropic axis (receptor-GR/GR/IGF-1) on thymopoiesis, homeostasis of thymocytes and peripheral T cells are presented.

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