Communications Medicine (Aug 2022)
Molecular epidemiology and antimicrobial resistance phenotype of paediatric bloodstream infections caused by Gram-negative bacteria
- Sam Lipworth,
- Karina-Doris Vihta,
- Tim Davies,
- Sarah Wright,
- Merline Tabirao,
- Kevin Chau,
- Alison Vaughan,
- James Kavanagh,
- Leanne Barker,
- Sophie George,
- Shelley Segal,
- Stephane Paulus,
- Lucinda Barrett,
- Sarah Oakley,
- Katie Jeffery,
- Lisa Butcher,
- Tim Peto,
- Derrick Crook,
- Sarah Walker,
- Seilesh Kadambari,
- Nicole Stoesser
Affiliations
- Sam Lipworth
- Nuffield Department of Medicine, University of Oxford
- Karina-Doris Vihta
- Nuffield Department of Medicine, University of Oxford
- Tim Davies
- Nuffield Department of Medicine, University of Oxford
- Sarah Wright
- Oxford University Hospitals NHS Foundation Trust
- Merline Tabirao
- Oxford University Hospitals NHS Foundation Trust
- Kevin Chau
- Nuffield Department of Medicine, University of Oxford
- Alison Vaughan
- Nuffield Department of Medicine, University of Oxford
- James Kavanagh
- Nuffield Department of Medicine, University of Oxford
- Leanne Barker
- Nuffield Department of Medicine, University of Oxford
- Sophie George
- Nuffield Department of Medicine, University of Oxford
- Shelley Segal
- Oxford University Hospitals NHS Foundation Trust
- Stephane Paulus
- Oxford University Hospitals NHS Foundation Trust
- Lucinda Barrett
- Oxford University Hospitals NHS Foundation Trust
- Sarah Oakley
- Oxford University Hospitals NHS Foundation Trust
- Katie Jeffery
- Oxford University Hospitals NHS Foundation Trust
- Lisa Butcher
- Oxford University Hospitals NHS Foundation Trust
- Tim Peto
- Nuffield Department of Medicine, University of Oxford
- Derrick Crook
- Nuffield Department of Medicine, University of Oxford
- Sarah Walker
- Nuffield Department of Medicine, University of Oxford
- Seilesh Kadambari
- Oxford University Hospitals NHS Foundation Trust
- Nicole Stoesser
- Nuffield Department of Medicine, University of Oxford
- DOI
- https://doi.org/10.1038/s43856-022-00161-0
- Journal volume & issue
-
Vol. 2,
no. 1
pp. 1 – 8
Abstract
Lipworth et al. conduct a molecular epidemiological analysis of Gram-negative bloodstream infections in children in Oxfordshire, England, over a 10-year period. The authors report E. coli as the main causative agent and observe a similar population structure to that seen in adult infections with a stable incidence of antimicrobial resistance.
