Nutrients (2020-05-01)

External Validation of Equations to Estimate Resting Energy Expenditure in 2037 Children and Adolescents with and 389 without Obesity: A Cross-Sectional Study

  • Giorgio Bedogni,
  • Simona Bertoli,
  • Ramona De Amicis,
  • Andrea Foppiani,
  • Alessandra De Col,
  • Gabriella Tringali,
  • Nicoletta Marazzi,
  • Valentina De Cosmi,
  • Carlo Agostoni,
  • Alberto Battezzati,
  • Alessandro Sartorio

DOI
https://doi.org/10.3390/nu12051421
Journal volume & issue
Vol. 12, no. 1421
p. 1421

Abstract

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We performed an external cross-validation study of 10 equations to estimate resting energy expenditure (REE) in 2037 children with and 389 without obesity. Inclusion criteria were Caucasian ethnicity, age ≤ 18 years, and availability of REE. REE was measured using indirect calorimetry. The correct classification fraction (CCF) of an equation was defined as the fraction of subjects whose estimated REE was within 10% of measured REE. The Molnár equation was the most accurate REE prediction equation with CCFs of 0.70 (95% CI 0.65 to 0.76) in girls without obesity, 0.64 (95% CI 0.61 to 0.66) in girls with obesity, 0.76 (95% CI 0.67 to 0.83) in boys without obesity, and 0.66 (95% CI 0.63 to 0.69) in boys with obesity. The Mifflin equation was the second most accurate equation with CCFs of 0.67 (95% CI 0.61 to 0.73) in girls without obesity, 0.61 (95% CI 0.58 to 0.64) in girls with obesity, 0.75 (95% CI 0.66 to 0.82) in boys without obesity, and 0.66 (95% CI 0.63 to 0.69) in boys with obesity.

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