Niclosamide targets the dynamic progression of macrophages for the resolution of endometriosis in a mouse model

Liang Zhao; Mingxin Shi; Sarayut Winuthayanon; James A. MacLean; Kanako Hayashi

doi:10.1038/s42003-022-04211-0

Communications Biology (Nov 2022)

Niclosamide targets the dynamic progression of macrophages for the resolution of endometriosis in a mouse model

Liang Zhao,
Mingxin Shi,
Sarayut Winuthayanon,
James A. MacLean,
Kanako Hayashi

Affiliations

Liang Zhao: School of Molecular Biosciences, Center for Reproductive Biology, Washington State University
Mingxin Shi: School of Molecular Biosciences, Center for Reproductive Biology, Washington State University
Sarayut Winuthayanon: School of Molecular Biosciences, Center for Reproductive Biology, Washington State University
James A. MacLean: School of Molecular Biosciences, Center for Reproductive Biology, Washington State University
Kanako Hayashi: School of Molecular Biosciences, Center for Reproductive Biology, Washington State University

DOI: https://doi.org/10.1038/s42003-022-04211-0
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 16

Abstract

Read online

In a mouse model of endometriosis, niclosamide is found to have potential therapeutic value through its fine regulations of the dynamic progression of macrophages.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal